Division of Carbohydrate Chemistry

ACS CARB

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Chen, Rui
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Chris Lawson
Member
Male
76 years old
About Me

I sold Glycomix Ltd to Carbosynth Ltd in 2016 and now work for Carbosynth as Scientific Director Biopolymers with the specific task of setting up a polysaccharide division in the company.  We have just completed a 'Toolbox' covering polysaccharide classification, applications, extraction/purification, structural analysis (primary, secondary, tertiary) and a review section covering polysaccharides from plants, algae, lichens, microbes, fungi and animal tissues.  This includes also a catalogue of polysaccharide products.

I formed Glycomix in 2007 following the successful sale of Dextra Laboratories, now a wholly owned subsidiary of New Zealand Pharmaceuticals and bring many years of experience to the management of chemistry and the life sciences. As joint founder of Dextra Laboratories I was a director of the team that developed Dextra into a seriously successful Glycobiology company with a catalogue of key research carbohydrates and a specialist custom synthesis business focussed on sugar chemistry.

As a senior research manager at Tate & Lyle Research I helped to bring a number of important projects to market including Xanthan Gum and Sucralose. I was also in the research team lead by Professor Sir Dai Rees in Edinburgh that demonstrated how polysaccharides form networks and highly organized structures in living tissues which have had enormous significance in the food and life science industries.

In the science of carbohydrates I have a particular interest in the chemistry of carbohydrate polymers with over 30 papers, books and patents to date.



Chruma, Jason
Member
About Me


Daron Freedberg
Member
Male
About Me


Demchenko, Alexei
Member
About Me

PROFESSIONAL EXPERIENCE

2008- Director of Graduate Studies in Chemistry and Biochemistry, University of Missouri – St. Louis

2007- Associate Professor of Chemistry and Biochemistry, University of Missouri – St. Louis

2001-2007 Assistant Professor of Chemistry and Biochemistry, University of Missouri – St. Louis

1998-2001 Research Associate (Boons), Complex Carbohydrate Research Center, University of Georgia

1995-1998 BBSRC Post-doctoral Research Fellow (Boons), University of Birmingham, UK

1993-1995 Research Associate (Kochetkov), Zelinsky Institute of Organic Chemistry, Moscow, Russia

 

EDUCATION

1988-1993 PhD in Organic Chemistry (Kochetkov), Zelinsky Institute of Organic Chemistry, Russia

1982-1988 Diploma in Chemical Engineering, Mendeleev University of Chemical Technology of Russia

 

RESEARCH INTERESTS

Stereocontrol and other aspects of chemical glycosylation. Expeditious strategies for the synthesis of complex oligosaccharides and glycoconjugates: chemoselectivity and orthogonality of modern glycosyl donors. Transition metal complexes in synthetic carbohydrate chemistry: direction of the stereoselectivity of glycosylation, temporary deactivation, etc. Fully synthetic therapeutics based on synthetic oligosaccharides and glycoconjugates (anti-cancer, anti-bacterial, anti-septic, etc.). Solid phase and surface chemistry: application to stereoselective glycosylation and rapid assembly of complex oligosaccharides and glycoconjugates.

 

SELECTED RECENT AWARDS AND HONORS

2009-2011 UM – St. Louis Senate Committee on Research, Chair

2007 New Investigator Award, Division of Carbohydrate Chemistry, ACS

2007- Editorial Advisory Board – Carbohydrate Research

2006- Member-at-Large, Executive Committee of the Division of Carbohydrate Chemistry, ACS

2005 CAREER Award, National Science Foundation

 

CURRENT RESEARCH SUPPORT

01/06-06/10 American Heart Association; BGIA (0660054Z), GIA (0855743G)

01/06-12/10 National Science Foundation; CAREER (CHE-0547566)

05/06-02/11 National Institutes of Health; NIGMS (2R15GM077170-02)

05/09-04/11 National Institutes of Health; NIAID (1R03AI067494-01A2)

09/09-08/13 National Institutes of Health; NIGMS (1R01GM090254-01) PI Keith Stine

 

SELECTED RECENT PUBLICATIONS (85 TOTAL)

P. Pornsuriyasak, C. Vetter, S. Kaeothip, et al. Chem. Commun., 2009, 6379-6381

S. Park, A. R. Parameswar, A. V. Demchenko, M. H. Nahm. Infect. Immun., 2009, 77, 3374-3379

P. Pornsuriyasak, S. C. Ranade, A. Li, M. C. Parlato, et al. Chem. Commun., 2009, 1834-1836

S. Kaeothip, P. Pornsuriyasak, N. P. Rath, A. V. Demchenko. Org. Lett., 2009, 11, 799-802

J. T. Smoot, A. V. Demchenko. J. Org. Chem., 2008, 73, 8838-8850

P. Pornsuriyasak, N. P. Rath, A. V. Demchenko. Chem. Commun., 2008, 5633-5635

L. K. Mydock, A. V. Demchenko. Org. Lett., 2008, 10, 2107-2110

L. K. Mydock, A. V. Demchenko. Org. Lett., 2008, 10, 2103-2106

M. C. Parlato, M. N. Kamat, H. S. Wang, K. J. Stine, A. V. Demchenko. J. Org. Chem., 2008, 73, 1716-1725

M. N. Kamat, C. De Meo, A. V. Demchenko. J. Org. Chem., 2007, 72, 6947-6955

M. N. Kamat, N. P. Rath, A. V. Demchenko. J. Org. Chem., 2007, 72, 6938-6946

A. F. G. Bongat, M. N. Kamat, A. V. Demchenko. J. Org. Chem., 2007, 72, 1480-1483

P. Pornsuriyasak, A. V. Demchenko. Chem. Eur. J., 2006, 12, 6630-6646

J. T. Smoot, P. Pornsuriyasak, A. V. Demchenko. Angew. Chem. Int. Ed., 2005, 44, 7123-7126

M. N. Kamat, A. V. Demchenko. Org. Lett., 2005, 7, 3215-3218

A. V. Demchenko, P. Pornsuriyasak, C. De Meo, N. N. Malysheva. Angew. Chem. Int. Ed., 2004, 43, 3069-3072

 

BOOKS EDITED

Handbook of Chemical Glycosylation, A. V. Demchenko Ed., Wiley-VCH, 2008

Frontiers in Modern Carbohydrate Chemistry, A. V. Demchenko Ed., ACS Symp. Ser., 960, 2007

 

 

 



Du, Minghui
Member

Duus, Jens
Member
About Me

Professor at DTU

Denmark



Eriks, Rozners
Member
About Me

Professor and Chair of Chemistry, Binghamton University (SUNY Binghamton)

Our research interests are in the chemistry and biochemistry of nucleic acids with a focus on elucidation of RNA’s structure and function. The research philosophy is to use organic chemistry as the enabling discipline to create unique model systems and tools for fundamental studies and practical applications in nucleic acid biochemistry, biophysics and biomedicine. The current projects include design, synthesis, and biophysical exploration of RNA analogs having non-phosphorous internucleoside linkages and development of novel RNA binders based on nucleobase-modified PNA for biomedical applications.



Forshage, Pamela
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About Me


French, Alfred
Member
About Me

The research of Al French concerns the 3-dimensional structures of carbohydrate molecules, especially cellulose and starch, studied either with computer modeling or, in collaboration, diffraction crystallography.  He is the current Chair-Elect of the Division of Cellulose and Renewable Materials, and in 2010 he received the 2009 Anselme Payen Award. He is a past Chair of the Division of Carbohydrate Chemistry, as well.



Gentry, Matthew
Member
About Me

Assistant Professor, Department of Molecular and Cellular Biochemistry, College of Medicine, University of Kentucky



Gervay-Hague, Jacquelyn
Member
About Me

Jacquelyn Gervay-Hague received a B.S. degree from The University of California, Los Angeles, in 1985 where she also earned a Ph.D. in 1990 under the direction of Professor Michael E. Jung. In 1990 she moved to Yale University as a National Institutes of Health Postdoctoral Fellow with Professor Samuel J. Danishefsky. In 1992, Professor Gervay-Hague joined the faculty in the Department of Chemistry at the University of Arizona and she was promoted to Associate Professor in 1998. In 2000, Professor Gervay-Hague worked as an on-sight consultant at Roche Bioscience in Palo Alto. And she was appointed Professor of Chemistry at University of California, Davis in 2001. In 2009, she assumed the position of Associate Vice Provost for Outreach and Engagement in the office of the Chancellor and Provost at UC, Davis. In 2011, Professor Gervay-Hague was appointed Chair of the Chemistry Department.



Gin, David Y.
Member
About Me

David Gin received his BSc in Chemistry at the University of British Columbia in 1989, where he performed summer undergraduate research under the direction of Prof. Tom Money. In 1989, he began his graduate studies in synthetic chemistry at the California Institute of Technology under the direction of Prof. Andrew Myers. After taking his PhD in 1994, he held a two-year NSERC postdoctoral appointment at Harvard under the guidance of Prof. E. J. Corey. Gin began his independent academic career in 1996 at the University of Illinois at Urbana-Champaign, where he remained for 10 years in the Chemistry Department, establishing a research program in natural product synthesis and reaction methodology development. In 2006, he moved his laboratory to the Memorial Sloan-Kettering Cancer Center, where he is currently Member and Tri-Institutional Professor. Gin’s research program focuses on the chemical synthesis of complex carbohydrates and bioactive alkaloids. Specific areas of his research program include the development of glycosylation reactions for the synthesis of novel adjuvants for cancer and infectious disease vaccines, as well as the development of hetero-annulation reactions for the synthesis of anti-tumor and anti-viral alkaloids.



Guerrini, Marco
Member
About Me

Head of the NMR Carbohydrate Centre of Institute for Chemical and Biochemical Research "G. Ronzoni", Milan - Italy. Main research activity is focused on the structure-activity relationship of glycosaminoglycans.



Hattori, Kazuyuki
Member
Male
About Me


Janetka, James
Member
About Me

Associate Professor, Department of Bicohemistry and Molecular Bioophysics, and Chemistry, Washington University in Saint Louis, School of Medicine

Co-founder, Fimbrion Therapeutics, Inc., Saint Louis MO

Co-founder, ProteXase Therapeutics, Inc., Saint Louis MO


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